WebDec 15, 2024 · Cyclin-dependent kinase 2 (CDK2) is a potential therapeutic target for the treatment of hearing loss and cancer. Previously, we identified AZD5438 and AT7519-7 …
Hedgehog 信号通路与癌症 MedChemExpress - 知乎 - 知乎专栏
WebFeb 23, 2024 · 因此,独特的基因可能调节正常垂体细胞分化的特定方面,如适当的时间。 2.2. pit1谱系正常垂体细胞的发育. pit1(也称为pou1f1)是pou结构域的转录因子,对于正常垂体细胞的末端细胞分化和基因表达至关重要,垂体细胞继续分泌神经内分泌激素prl, … WebMar 21, 2024 · GeneCards Summary for PMAIP1 Gene. PMAIP1 (Phorbol-12-Myristate-13-Acetate-Induced Protein 1) is a Protein Coding gene. Diseases associated with PMAIP1 include Leukemia and Colorectal Cancer . Among its related pathways are Intrinsic Pathway for Apoptosis and Gene expression (Transcription) . billy sims bbq coupons
CCND2 cyclin D2 - NIH Genetic Testing Registry (GTR)
WebMar 2, 2024 · 基因测序示患儿ccnd2基因第5外显子存在c.820g>t, p.e274*杂合无义变异,诊断为巨脑症-多小脑回-多指(趾)畸形-脑积水综合征3型,扩大了ccnd2基因变异谱。. 患儿 男,1岁,因“大运动发育落后、不会坐”于2024年12月就诊于郑州大学附属儿童医院,主要 … WebDec 15, 2024 · Cyclin-dependent kinase 2 (CDK2) is a potential therapeutic target for the treatment of hearing loss and cancer. Previously, we identified AZD5438 and AT7519-7 as potent inhibitors of CDK2, however, they also targeted additional kinases, leading to unwanted toxicities. Proteolysis Targeting Chimeras … WebSep 12, 2024 · 摘要: 竞争性内源RNA(competing endogenous RNA,ceRNA)是一种新的转录后RNA相互调控机制,越来越多的研究发现长链非编码RNA(long non-coding RNA,lncRNA)、环状RNA(circular RNA,circRNA)和假基因(pseudogenes)可以与微小RNA(microRNA,miRNA)竞争,影响靶RNA的稳定性或翻译 ... cynthia cruz