WebFeb 22, 2007 · We originally identified collagen triple helix repeat containing-1 (Cthrc1) in a screen for differentially expressed genes in normal versus balloon-injured arteries. 1 In the vasculature, Cthrc1 expression is limited to injured tissue, where it is induced abundantly in adventitial fibroblasts and neointimal smooth muscle cells (SMCs). … Web作者观察到Cthrc1只在CF中而不在其他心肌细胞中表达,因此想要探讨Cthrc1在CF中的功能作用。 文中通过Cthrc1敲除小鼠(KO)研究发现在生长发育成年过程中大小、体积、 …
Cthrc1, a Novel Circulating Hormone Regulating Metabolism
WebThe highest level of Cthrc1 binding was observed in the liver. Conclusions: Cthrc1 has characteristics of a circulating hormone generated from the anterior pituitary, … Web胶原三螺旋重复蛋白-1(collagen triple helix repeat containing-1, CTHRC1) 是一种具有血管损伤修复作用的分泌型蛋白,参与血管重构、成骨细胞形成以及创伤修复。CTHRC1通过促进细胞迁移、血管形成参与肿瘤病理进 … tiwal.com
Cancer-Associated Stromal Fibroblast-Derived Transcriptomes …
WebDec 1, 2001 · A condition characterized by a metaplastic change in which normal esophageal squamous epithelium is replaced by a columnar and intestinal-type epithelium. Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement … WebDec 7, 2012 · Collagen triple helix repeat containing-1 (CTHRC1) is a secreted protein involved in vascular remodeling, bone formation and developmental morphogenesis. CTHRC1 has recently been shown to be expressed in human cancers such as breast cancer and melanoma. In this study, we show that CTHRC1 is highly expressed in … WebCollagen triple helix repeat containing 1 is a protein that in humans is encoded by the CTHRC1 gene. Function. This locus encodes a protein that may play a role in the cellular … tiwala breezy lyrics