Dynein intermediate chain 1
WebThus, IC1 is a novel dynein intermediate chain distinct from IC2 and IC3 and may be a multifunctional protein. The thioredoxin-related part of IC1 is more closely related to those of two redox-active Chlamydomonas light chains than thioredoxin. Antibodies were prepared against the N-terminal and middle domains of IC1 expressed as His-tagged ...
Dynein intermediate chain 1
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WebPTHR12442 DYNEIN INTERMEDIATE CHAIN 1 hit; PROSITE. View protein in PROSITE; PS50082 WD_REPEATS_2 1 hit; PS50294 WD_REPEATS_REGION 1 hit; Pfam. View … WebJul 21, 2010 · Background Intracellular transport of cargoes including organelles, vesicles, signalling molecules, protein complexes, and RNAs, is essential for normal function of eukaryotic cells. The cytoplasmic dynein complex is an important motor that moves cargos along microtubule tracks within the cell. In mammals this multiprotein complex includes …
WebAll lanes : Anti-Dynein intermediate chain 1/DNAI1 antibody [EPR11222] (ab156567) at 1/1000 dilution Lane 1 : Fetal brain lysate Lane 2 : Human hypothalamus lysate Lysates/proteins at 10 µg per lane. Secondary All … WebDec 4, 2014 · • Design and execute programs for intermediate, adult, and athletic population in individual and group settings ... Jan 2013 - Jan 2015 2 years 1 month. …
WebWe show that human dynein light intermediate chain (DLIC) binds the N-terminal RH1 domain of JIP3, its paralog JIP4, and the lysosomal adaptor RILP. A point mutation in RH1 abrogates DLIC binding without perturbing the interaction between JIP3’s RH1 domain and kinesin heavy chain. Characterization of this separation-of-function mutation in ... WebDec 8, 2024 · Also known as. PCD; DIC1; ICS1; CILD1. Summary. This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the …
WebAug 26, 2024 · The dynein-1 light-intermediate chain has a long disordered C-terminal extension (dashed line) containing a helix that binds to dynein-1 cargo adaptors (Schroeder, C. M. et al. Elife.
WebThe cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light … prohealthsysWebAug 1, 2011 · Dyn2 has sequence similarity to the LC8 family of dynein light chains. The putative yeast dynein LC gene, DYN2/YDR424C/SLC1, was originally identified by searching the yeast genome for sequences similar to those of the human light chain (Dick et al., 1996b).The Dyn2 amino acid sequence is most similar to the highly conserved LC8 … l6 0byWebCytoplasmic Dynein Intermediate chain was immunoprecipitated from 0.35 mg Rat brain tissue lysate 10 µg with ab23905 at 1/30 dilution (2 µg in … l6 4byWebNov 7, 2005 · Cytoplasmic dynein 2 light intermediate chain 1, D2LIC, LIC3: Open in a separate window. 13 well-established cytoplasmic dynein components are currently identified; other components may exist. The former mouse and human gene nomenclatures are shown along side the revised nomenclature for both species. Also shown are the … l6 2ad property for saleWebJan 20, 2024 · Each dynein adopts an extended and slanted configuration on the doublet microtubule in which the motor domains of β-HC and γ-HC closely associate with the heavy chain tail domains and auxiliary ... prohealthus instagramWebGene ID: 128046204, updated on 28-Feb-2024. Summary Other designations. cytoplasmic dynein 1 intermediate chain 1 l6 arrowhead\\u0027sWebHere, using mRNA arrays and protein analysis, we show that the dynein subunit, DYNC1LI2 (dynein, cytoplasmic 1 light intermediate chain 2) is downregulated in cystinosis, a lysosomal storage disorder caused by genetic defects in CTNS (cystinosin, lysosomal cystine transporter). prohealthtx