Fnip2
WebWe report here a mutation in the folliculin-interacting protein 2 (FNIP2) gene in the Weimaraner dog that results in hypomyelination of the brain and a tract-specific myelin defect in the spinal cord. This myelination disruption results in a notable tremor syndrome from which affected dogs recover with time. WebThe deduced 1,114-amino acid protein shares 49% identity with FNIP1. Quantitative real-time PCR detected variable FNIP2 expression in most tissues examined, with highest …
Fnip2
Did you know?
WebMar 3, 2024 · FLCN forms complexes with two large interacting proteins, FNIP1 and FNIP2. Structural studies have shown that both FLCN and FNIPs contain longin and differentially expressed in normal versus neoplastic cells (DENN) domains, typically involved in the regulation of small GTPases. WebA second folliculin-interacting protein FNIP2 was discovered through bioinformatics searches for sequences similar to FNIP1 ( 12, 13 ). Similar to FNIP1, FNIP2 was found …
http://shanghaipasteur.cas.cn/zhxw/202406/t20240624_6715152.html WebPrEST Antigen FNIP2 [Catalog No.: ATL-APrEST84063] Toggle menu. Compare ; Phone: 760-431-4600 / Fax: 760-431-4604; Sign in or Register; Cart 0. Search. CURRENT PROMOTIONS. WORLDWIDE DISTRIBUTION. CONTACT US. Neurodegeneration Products; CUSABIO dashboard; Fukushima Cancer Gene Overexpressing Cell Lines;
WebJan 18, 2024 · Surprisingly, the absence of FLCN or its binding partners FNIP1/FNIP2 induces interferon response genes independently of interferon. Mechanistically, FLCN loss promotes STAT2 recruitment to chromatin and slows cellular proliferation. Our integrated analysis identifies STAT1/2 signaling as a novel target of FLCN in renal cells and BHD … Webin kidney, the Fnip2 expression level, which is commensurate with that of Fnip1, might maintain Fnip function in Fnip1-deficient kidneys, and therefore, double inactivation …
WebFNIPL folliculin interacting protein 2 Limitations This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt. Customers Who Viewed This Item Also Viewed... Folliculin Antibody NBP1-44995 • • • (1 Publication ) Species: Hu, Mu
WebNov 11, 2024 · For example, in chicken (Gallus domesticus), lncRNA-FNIP2 cis-regulates LPIN1, thereby regulating hepatic adipogenesis . In blunt snout bream ( Megalobrama amblycephala ), lncRNA-MSTRG.6100 regulates two upstream cis targets, the genes encoding histone-lysine N -methyltransferase SET and MYND domain-containing protein … rd bank of barodaWebT carriers of rs2291007 have decreased expression of FNIP2 in peripheral blood, and importantly, FNIP2 mRNA levels strongly associate with decreased obesity-related … rdbbuf symfowareWebAnti-FNIP2 antibody Description Rabbit polyclonal to FNIP2 Host species Rabbit Specificity ab106611 is predicted to not cross-react with FNIP1. Tested applications Suitable for: … sinbad and the seven seas animeWebAug 31, 2024 · The lysosomal folliculin (FLCN) complex (LFC) consists of the inactive Rag dimer, the pentameric scaffold Ragulator, and the FLCN:FNIP2 (FLCN-interacting protein 2) GTPase activating protein... rdb aof 是什么WebFLCN-FNIP2 adopts an extended conformation with two pairs of heterodimerized domains. The Longin domains heterodimerize and contact both nucleotide binding domains of the … sinbad and phil hartman movieWebJun 24, 2024 · It was showed that the co-transfection between wild type FNIP2 3′UTR and miR-24-3p could reduce the luciferase activity , indicating a target relationship between FNIP2 and miR-24-3p. qRT-PCR and the Western Blot results showed that miR-24-3p does have a posttranscriptional regulation on FNIP2, which miR-24-3p downregulated FNIP2 … rdb californiaWebAcronym. Definition. FNIP. Fichier National des Incidents de Paiement (French: National File of Payment Incidents) FNIP. First Nation Information Project (Canada) rd bath beyond