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Hif 1 alpha uniprot

Web21 de mar. de 2024 · HIF1A (Hypoxia Inducible Factor 1 Subunit Alpha) is a Protein Coding gene. Diseases associated with HIF1A include Retinal Ischemia and Enchondromatosis, Multiple, Ollier Type.Among its related pathways are Signaling by PTK6 and Regulation of activated PAK-2p34 by proteasome mediated degradation.Gene … WebCharacterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins. Biochem Biophys Res Commun 260, 557-561. Tanimoto, K., Makino, Y., Pereira, T., and Poellinger, L. (2000). Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein.

HIF-1alpha monoclonal antibody Immunohistochemistry, Western ...

WebHypoxia-inducible factor-1 (HIF1) is a basic helix-loop-helix (bHLH)-PER-ARNT-sim (PAS) transcription factor that plays a role in the cellular response to hypoxia. HIF1 is a heterodimer of an HIF1-alpha and HIF1-beta subunit. During normoxia, HIF-1alpha is regulated by ubiquitination and interaction with the von-Hippel-Lindau tumor suppressor ... Web27 de fev. de 2024 · UniProt Q16665 - HIF1A_HUMAN. Gene HIF1A Modification Unmodified View Product On Supplier's Website Request a Quote ... HIF1, BHLHE78, MOP1, PASD8, HIF-1A, HIF-1alpha, HIF1-ALPHA, HIF-1-alpha. View additional product information. Experiments from the literature. Loading published images for this product … chins positioning and attachment https://urlocks.com

RCSB PDB - 1H2K: Factor Inhibiting HIF-1 alpha in complex with …

WebResearch Information. HIF-1α Antibody (28b) is an IgG κ mouse monoclonal HIF-1 alpha antibody (also designated HIF1A antibody or HIF-1 alpha antibody) suitable for the … Web17 de jan. de 2003 · The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent hydroxylation. Under normoxic conditions, hydroxylation … Web6 de out. de 2024 · HIF is a transcription factor that plays an essential role in the cellular response to low oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In immunity, infected and inflamed tissues are often hypoxic, and HIF helps immune cells adapt. HIF-α stabilization ca … grannys tamales in humble

HIF1A Antibody Affinity Biosciences

Category:HIF1A Human ELISA Kit - Invitrogen - Thermo Fisher Scientific

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Hif 1 alpha uniprot

RCSB PDB - 4ZPR: Crystal Structure of the Heterodimeric HIF …

WebAnti-HIF-1 alpha antibody [H1alpha67] (ab1) ... Information by UniProt; ... Immunohistochemical analysis of paraffin-embedded human lung tissue labeling Neurogranin with ab273444 at 1/10000 (0.111 ug/ml) dilution followed by a ready to use LeicaDS9800 (Bond® Polymer Refine Detection) was used. Web12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent hydroxylation. Under normoxic conditions, …

Hif 1 alpha uniprot

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Web9 de mai. de 2002 · Crystal structure of a hydroxylated HIF-1 alpha peptide bound to the pVHL/elongin-C/elongin-B complex. ... Hypoxia-inducible factor 1 ALPHA: D: 34: N/A: Mutation(s): 1 : UniProt & NIH Common Fund Data Resources: Find proteins for Q16665 (Homo sapiens) Explore Q16665 . Go to UniProtKB: Q16665. PHAROS: Q16665. WebWe investigated the impact of inhibiting HIF-1α transcriptional activity on cytotoxic immune cell infiltration into B16-F10 melanoma. We showed that tumors expressing a deleted form of HIF-1α displayed increased levels of NK and CD8 + effector T cells in the tumor microenvironment, which was associated with high levels of CCL2 and CCL5 ...

WebGene summary (Entrez)i. Useful information about the gene from Entrez. This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a … WebThis kit recognizes Human HIF-1α in samples. No significant cross-reactivity or interference between Human HIF-1α and analogues was observed. Both intra-CV and inter-CV are < 10%. This ELISA kit applies to the in vitro quantitative determination of Human HIF-1α concentrations in serum, plasma and other biological fluids.

WebImmunocytochemistry analysis of HIF1A in immersion fixed HeLa human cervical epithelial carcinoma cell line treated with DFOA. Samples were incubated in HIF1A monoclonal antibody (Product # MA1-16504) using a dilution of 1 µg/mL followed by donkey anti-rabbit secondary antibody and counterstained with DAPI (blue). WebUniProt website fallback message If you are not seeing anything on this page, it might be for multiple reasons: You might have JavaScript disabled: make sure to ...

Web10 de abr. de 2024 · Summary. This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a …

WebRAR相关孤儿受体 （英語： RAR-related orphan receptor ， RORs ）是 核受体 的一个家族，是 细胞内 转录因子 的一员 [1] [2] 。. 有三个ROR家族成员： ROR-α 、 -β 和 -γ 分别由基因 RORA 、 RORB 、 RORC 编码。. RORs的不寻常之处在于它们是以单体形式结合到 激素 … granny steam下载WebBackground: HIF-1 alpha/HIF1A. This biotinylated peptide includes a sequence from human Hypoxia-Inducible Factor 1-alpha (HIF-1 alpha ) with an unmodified (non-hydroxylated) proline residue corresponding to proline 564 in UniProt Q16665. The peptide is not efficiently ubiquitinated by a VHL/Elongin B/Elongin C/CUL2/RBX complex (catalog … chin spots causesWebA fusion protein including amino acids 530 - 825 of the mouse HIF-1 alpha protein [UniProt# Q61221]. Purification Purified by antigen-affinity chromatography Conjugation … granny steam pageWeb12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent hydroxylation. Under normoxic conditions, hydroxylation of proline residues triggers destruction of its alpha-subunit while hydroxylation of Asn (803) in the C-terminal … granny steam unlocked downloadWeb19 de mar. de 2002 · Disruption of the Hif-1 alpha/p300 interaction has been linked to attenuation of tumor growth. To delineate the structural basis for this interaction, ... granny steam codeWeb12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent … chins portlandWebMonoclonal Anti-HIF2 alpha antibody produced in mouse. clone GT125, affinity isolated ... UniProt accession no. Q16665. shipped in. wet ice. storage temp. −20°C. Gene ... Hif1a(15251) rat ... Hif1a(29560) Description. General description. Hypoxia-inducible factor-1 (HIF-1) is a 120kD basic helix-loop-helix protein that belongs to the PAS ... granny steam game