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Stathmin-3

WebStathmin (also known as Oncoprotein 18) is a small cytosolic protein that binds to tubulin dimers rather than to microtubules. Each stathmin binds two tubulin dimers, preventing … WebPharos : Target Details - STMN3 Jump to section: close Descriptive Data Protein Summary Protein Classes IDG Development Level Summary Expression Data Protein Sequence and Structure Related Tools Behavioral Data Approved Drugs Active Ligands Protein-Protein Interactions Nearest Tclin Targets Pathways Predicted Viral Interactions Phenotypic Data

STMN1 Gene - GeneCards STMN1 Protein STMN1 …

WebMar 29, 2024 · Official Full Name stathmin 2 provided by HGNC Primary source HGNC:HGNC:10577 AllianceGenome:HGNC:10577 Gene type protein coding RefSeq status Organism Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; … tim mcafee seattle https://urlocks.com

The role of stathmin in the regulation of the cell cycle - PubMed

WebMay 1, 2024 · In the current study, we assessed Stathmin as an indicator of PI3K pathway activity in HPV-negative HNSCC. We compared Stathmin IHC to pAKT1 and PTEN IHC, as … WebStathmin-3 Gene Stmn3 Status UniProtKB reviewed (Swiss-Prot) Organism Mus musculus (Mouse) Amino acids 180 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Add a publication Entry feedback Function WebStore at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. tim mcafee

Stathmin 2 protein - 其他重组蛋白 - 深圳欣博盛生物科技有限公司

Category:Stathmin Antibody Cell Signaling Technology

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Stathmin-3

Stathmin: A Tubulin-Sequestering Protein Which Forms a Ternary …

WebTitle: Specific serine-proline phosphorylation and glycogen synthase kinase 3β-directed subcellular targeting of stathmin 3/Sclip in neurons. Studies suggest that a STAT3-SCLIP … WebStathmin has been investigated as a tumor biomarker because it appear to be associated with tumorigenesis; however, the effect of stathmin in lung adenocarcinoma (LAC) remains poorly understood.

Stathmin-3

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WebThese data support a stathmin-dependent pathway of As2O3-mediated cell death in solid tumor cells, and indicate that stathmin is a target of the PI3K/Akt pathway in cervical cancer cells. All these results may provide a rationale for improving the efficacy of As2O3 as a therapeutic agent through combination treatment with stathmin inhibition or ... WebStathmin Antibody detects endogenous levels of total stathmin protein. The antibody does not cross-react with related proteins such as SCG10, SCLIP and RB3. Species Reactivity: …

WebMar 17, 2024 · Scientists have found that TDP-43 is essential for proper maturation of the pre-mRNA encoding stathmin-2, a protein necessary for the outgrowth of neurons’ axons during development and regeneration following any injury. In a paper in Science, researchers led by a group at the University of California, San Diego, and including Cathleen Lutz ... WebStathmin, a key oncoprotein, was proved to be a new PRL-3 associated protein. Notably, co-immunoprecipitation assays in both endogenous CRC cell lines and CRC tissues indicated …

WebMar 21, 2024 · STMN1 (Stathmin 1) is a Protein Coding gene. Diseases associated with STMN1 include Acute Leukemia and Leukemia . Among its related pathways are Signaling by ERBB4 and ERK Signaling . Gene … WebApr 11, 2024 · Stathmin 1 acts as a microtubule destabilizer by interacting with αβ-tubulin heterodimers and inhibiting microtubule polymerization. Stathmin 1 has two functional domains: The N-terminus domain facilitates microtubule depolymerization, and the C-terminus domain is indispensable for tubulin dimer binding and sequestering [12].

WebOct 19, 2024 · Recently, this TDP-43 suppressor function was specifically implicated in suppressing a cryptic early polyadenylation site in the pre-mRNA for the protein stathmin-2 (STMN2). Loss of TDP-43 allows incorporation of a premature poly A tail, resulting in a truncated and nonfunctional form of STMN2 ( 15, 16 ).

WebApr 6, 2024 · About STATHMIN-2 and TDP-43 STATHMIN-2 (STMN2) is a well-validated protein important for neural repair and axonal stability, the expression of which is significantly decreased in nearly all ALS ... tim mcaloon law office of timothy p. mcaloonStathmin-3 is a protein that in humans is encoded by the STMN3 gene. parks auction and land division tennesseeWebMay 18, 2010 · Tubulin is able to switch between a straight microtubule-like structure and a curved structure in complex with the stathmin-like domain of the RB3 protein (T (2)RB3). GTP hydrolysis following microtubule assembly induces protofilament curvature and disassembly. The conformation of the labile tubulin heterodimers is unknown. parks auburn wa